Metabolomics: New hope for personalized medicine, advantages, limitations and future prospective 1/2
Where: Building 9 Lecture hall 1
Credit: 2
Description
An offering with a pre-registration process
Metabolomics presents a snapshot of the metabolic dynamics that reflect the response of the human body to pathophysiological stimuli and/or genetic modifications and the surrounding environment; giving it an advantage as a disease diagnostic tool. Furthermore, in many ways transcriptomic, genomic, and proteomic changes are upstream of the final physiology of the cell, whereas the metabolic profile is likely closer in response to the disease process.
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Abdul-Hamid Emwas
Abdul-Hamid Emwas, is a staff scientist at Imaging and Characterization Core Lab, KAUST. Dr. Emwas received a Ph.D. in Physical Chemistry from the University of New Brunswick, Canada, and his M.Sc. in Biophysical Chemistry, from the University of Bergen, Bergen, Norway. He graduated earlier with B.Sc. (Chemistry), from the University of Bir-Zeit, Bir-Zeit, Palestine. His research interest is in developing new NMR and EPR approaches for protein and DNA structural analysis. Currently, Dr. Emwas’ research focus is on developing, optimizing and standardizing novel NMR metabolomics approaches that can be used as a diagnostic and prognostic tool for human diseases.
Dalila Bensaddek
Dalila Bensaddek obtained her Ph.D. in mass spectrometry at the Michael Barber Centre for mass spectrometry, in FTMS (high-resolution MS) working on single peptides and single purified proteins. Then Dr. Bensaddek worked on proteomics and LC-MS in Geneva Switzerland (Denis Hochstrasser) and phospho-proteomics in Boston (Hanno Steen) before coming back to Europe to do high throughput proteomics in Dundee, where she managed the quantitative proteomics laboratory and expanded by experience in all things proteomics including on model organisms, cell lines, and stem cells. Finally, Dr. Dalila moved to work as an application specialist with Bruker in life sciences and proteomics before joining KAUST, where she is currently in-charge of set-up MS-based metabolomics platform.
Najeh Kharbatia
Najeh Kharbatia is a staff scientist in the organic team at KAUST’s Analytical Core Laboratory. He earned a master degree in mass spectrometry from Stevens Institute of Technology (USA). Najeh joined KAUST in 2013 coming from Agilent Technologies. He employs GC/MS and LC/MS based metabolomics platforms to study metabolites distribution in plants, bacteria, parasites, and human’ tissues and fluids. Najeh Kharbatia was the first to lead the effort in establishing metabolomics and lipidomics capabilities at ACL to support KAUST researchers.
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