Where: Building 9 Lecture hall 1
Credit: 1
Description
Lecture by Claus-Michael Lehr, Professor at Saarland University and co-founder and head of the Drug Delivery department at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS).
ABOUT THIS EVENT
Infectious diseases are on the rise and increasing challenge to human health with mortality rates predicted to soon exceed those of cancer and other diseases. While antimicrobial resistance is increasing, the number of new antibiotics and even the number of companies engaging in those is decreasing. Besides the need for new targets and molecules for anti-infective compounds, such as e.g. path blockers, there is also a need to deliver those across biological barriers preventing access to the target site. Relevant barriers in this context are the body’s outer epithelia, in particular of the gut, the skin, and the lung, but also host cell membranes, the bacterial cell envelope as well as non-cellular barriers, such as mucus and bacterial biofilm. The lecture will provide an introduction into this exciting field of research with a focus on novel nanomedicines as innovative human cell- and tissue models as an alternative to animal testing.
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Claus-Michael Lehr
Claus-Michael Lehr is a Professor at Saarland University as well as co-founder and head of the department Drug Delivery at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). Lehr has also been the co-founder of Across Barriers GmbH and acts as CEO of PharmBioTec GmbH, a not-for-profit contract research subsidiary of Saarland University. The research theme of his team is non-invasive drug delivery across biological barriers, in particular, the epithelia of the gastrointestinal tract, the skin, and the lungs. Recently, this has expanded to microbial barriers. He is (co)author of more than 350 papers with >12.000 citations (h‐index = 66). Recently, the British magazine “The Medicine Maker” rated him, for the third time, as one of the top 100 most influencing drug researchers in the world.
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