Where: Bldg 20 Auditorium
Credit: 2
Description
The concept of time becomes a concrete and palpable “object” with our collection of memories. When our ability to collect and preserve memories is at risk, separating the past from fiction becomes hard and our connection with loved ones and ourselves is lost.
Professor Karen Ashe works on unveiling the mechanisms of Alzheimer's disease with an attempt to reverse memory loss associated with it. Her team showed that by controlling the Tau protein, which is responsible for miscommunication between nerve cells, dementia stopped and the memory of mice improved. This work was published in Nature Medicine.
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Karen Ashe
Karen Ashe, MD, PhD, is the director of the N. Bud Grossman Center for Memory Research and Care and holds the Edmund Wallace and Anne Marie Tulloch Chairs in Neurology and Neuroscience at the University of Minnesota. She received her MD from Harvard University, and her PhD from MIT. Her mouse models of Alzheimer's disease have been used the world over for validating genetic linkage studies, for understanding disease pathogenesis, for seeking markers of early disease processes, and for testing candidate therapies. Among many honors, she has received the MetLife Award for Alzheimer’s disease research, the Potamkin Prize of the American Academy of Neurology, the Khalid Iqbal Lifetime Achievement Award of the Alzheimer’s Association, and is a member of the National Academy of Medicine.
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